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1.
Increased risk for severe outcome in teenagers with multisystem inflammatory syndrome temporally associated with Covid-19 mimicking Kawasaki disease: is there an age-related Achilles heel?
Mormile, Raffaella.
Minerva Pediatr (Torino) ; 2021 Apr 19.
Article in English | MEDLINE | ID: covidwho-2300397
2.
IL-6 inhibitors for critically ill patients with SARS-CoV-2 pneumonia: a suitable treatment for everyone or only for a few?
Mormile, Raffaella.
Minerva Pediatr (Torino) ; 75(1): 131-132, 2023 02.
Article in English | MEDLINE | ID: covidwho-2272920

Subject(s)
COVID-19 , Pneumonia , Humans , SARS-CoV-2 , Interleukin-6 Inhibitors , Critical Illness/therapy
3.
Thrombosis with thrombocytopenia after vaccination with the ChAdOx1 nCoV-19 vaccine (Oxford-AstraZeneca): implications of gender-specific tissue-factor gene polymorphisms?
Mormile, Raffaella.
Expert Rev Clin Pharmacol ; : 1-3, 2022 Dec 06.
Article in English | MEDLINE | ID: covidwho-2233473
4.
High degree atrioventricular block and COVID-19 infection: a two player match?
Mormile, Raffaella.
Expert Rev Cardiovasc Ther ; 20(10): 783-786, 2022 10.
Article in English | MEDLINE | ID: covidwho-2051005

Subject(s)
Atrioventricular Block , COVID-19 , Humans , Atrioventricular Block/etiology , Atrioventricular Block/therapy , COVID-19/complications , Transforming Growth Factor beta1 , Electrocardiography
5.
Il-6, Il-1ß and cytokine-targeted therapy for COVID -19 patients: two more reasons to take into account statins?
Mormile, Raffaella.
Expert Rev Cardiovasc Ther ; 20(3): 161-163, 2022 03.
Article in English | MEDLINE | ID: covidwho-1758537

Subject(s)
COVID-19 Drug Treatment , Hydroxymethylglutaryl-CoA Reductase Inhibitors , Cytokines , Humans , Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
6.
Obesity and Severe COVID-19 in the Young: Is Downregulation of miR-126 a Piece of the SARS-COV2 Pathogenicity Puzzle?
Mormile, Raffaella.
Arch Med Res ; 53(2): 228-230, 2022 02.
Article in English | MEDLINE | ID: covidwho-1739544

Subject(s)
COVID-19 , MicroRNAs , Down-Regulation , Humans , MicroRNAs/genetics , Obesity/complications , Obesity/genetics , RNA, Viral , SARS-CoV-2 , Virulence
7.
Myocarditis and pericarditis following mRNA COVID-19 vaccination in younger patients: is there a shared thread?
Mormile, Raffaella.
Expert Rev Cardiovasc Ther ; 20(2): 87-90, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1703307

ABSTRACT

Rare cases of myocarditis and pericarditis after COVID-19 mRNA vaccination have been recently reported in male adolescents and young adults. Acute myocarditis and pericarditis following COVID-19 mRNA vaccination in male adolescents and young adults may be connected with age-related lower levels of T-bet and PD-1 in predisposed individulas with T-bet polymorphisms by the release od autoreactive CD8+CTL. Upregulatiomn of T-Bet and PD-1 by estrogen might explai the higher incidence of men developing myocarditis or pericarditis in comparison to women.


Subject(s)
COVID-19 , Myocarditis , Pericarditis , Adolescent , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Female , Humans , Male , Myocarditis/complications , Pericarditis/epidemiology , Pericarditis/etiology , RNA, Messenger , Vaccination/adverse effects , Young Adult
8.
COVID-19 myocarditis and lasting heart damage: is deregulation of the Beclin1-Survivin axis the critical step of pathogenesis?
Mormile, Raffaella.
Expert Rev Cardiovasc Ther ; 19(8): 681-683, 2021 08.
Article in English | MEDLINE | ID: covidwho-1307447
9.
Diabetes and susceptibility to COVID-19: may miR-146a make the difference between life and death?
Mormile, Raffaella.
Minerva Endocrinol (Torino) ; 46(3): 363-365, 2021 09.
Article in English | MEDLINE | ID: covidwho-1168363

Subject(s)
COVID-19 , Diabetes Mellitus , MicroRNAs , Genetic Predisposition to Disease , Humans , SARS-CoV-2
10.
Covid-19 and kawasaki disease: is there a need for revising treatment guidelines?
Mormile, Raffaella.
Minerva Pediatr ; 2020 Oct 27.
Article in English | MEDLINE | ID: covidwho-892550
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